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Obwohl diese Studien in indexierten Fachzeitschriften verffentlicht sind, bleibt die unabhngige Replikation durch andere Forschungsgruppen unzureichend, um endgltige Schlussfolgerungen zur therapeutischen Wirksamkeit beim Menschen zu ziehen

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The influence on brain enzymes (other than brain ChE), liver enzymes such as ChE (inhibition), microsomal cytochrome P-450 activity (decrease), drug-metabolizing enzyme activity, and UDP-glucuronyl transferase (no influence), and many other enzyme systems were studied

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